Mercury (Hg<sup>2+</sup>) and benzo[a]pyrene (BaP) are ubiquitous and persistent pollution with a number of toxicities in bivalve molluscs. Here, the toxicological responses in the gills of Manila clams, Ruditapes philippinarum, to Hg<sup>2+</sup> (10 μg L<sup>-1</sup>), BaP (<em>3</em> μg L<sup>-1</sup>), and their combination have been analysed utilizing transcriptomics and metabolomics approaches.
Comparisons of the transcriptomes and metabolomes of Hg<sup>2+</sup>-and/or BaP-treated clams with management animals revealed the involvement of the detoxing metabolism, immune defence, energy-related pathways, and osmotic regulation in the stress response of R. philippinarum.
Exposure to Hg<sup>2+</sup> alone primarily enhanced the detoxing and power metabolic pathways by considerably growing the expression of genes related to heat-shock <em>proteins</em> and oxidative phosphorylation. However, co-exposure to Hg<sup>2+</sup> and BaP triggered better immunotoxicity and disrupted detoxing metabolism, the <em>TCA</em> cycle, glycolysis, and ATP era.
The expression ranges of cytochrome P450 1A1 (CYP1A1), multidrug resistance-associated <em>protein</em> 1 (MRP1), and myosin (MYO), and the exercise of electron transport system (ETS) in gills have been detected, supporting the underlying poisonous mechanisms of Hg<sup>2+</sup> and BaP. We counsel that the presence of BaP enhances the toxicity of Hg<sup>2+</sup> by 1) hampering the detoxing of Hg<sup>2+</sup>, 2) growing the immunotoxicity of Hg<sup>2+</sup>, and <em>3</em>) constraining power availability for clams.
Oleic Acid and Eicosapentaenoic Acid Reverse Palmitic Acid-induced Insulin Resistance in Human HepG2 Cells by way of the Reactive Oxygen Species / JUN Pathway
The monounsaturated fatty acid (MUFA) oleic acid (OA) has beforehand been proven to reverse saturated fatty acid palmitic acid (PA)-induced hepatic insulin resistance (IR). However, its underlying molecular mechanism is unclear. In addition, earlier research have additionally proven that the ω-<em>3</em> polyunsaturated fatty acid (PUFA) eicosapentaenoic acid (EPA) reverses PA-induced muscle IR, however whether or not EPA performs the identical function in hepatic IR and its potential mechanism concerned want to be additional clarified. Here, we confirmed that EPA reversed PA-induced IR in HepG2 cells and in contrast the proteomic modifications after remedy with completely different free fatty acids (FFAs).
A complete of 2<em>3</em>4 <em>proteins</em> have been decided to be differentially expressed after MUFA remedy. Their features have been primarily associated to responses to stress and endogenous stimuli, lipid metabolic course of, and <em>protein</em> binding. For PUFA remedy, the PA-induced expression modifications of 1<em>3</em>26 <em>proteins</em> could possibly be reversed by EPA remedy, 415 of which have been mitochondrial <em>proteins</em>, with most of the practical <em>proteins</em> concerned in oxidative phosphorylation (OXPHOS) and tricarboxylic acid (<em>TCA</em>) cycle.
Mechanistic research revealed that the <em>protein</em> encoded by JUN and reactive oxygen species (ROS) play a job in OA- and EPA-reversed PA-induced IR, respectively. EPA or OA alleviated PA-induced irregular adenosine triphosphate (ATP) manufacturing, ROS era, and calcium (Ca<sup>2+</sup>) content material. Importantly, H<sub>2</sub>O<sub>2</sub>-activated manufacturing of ROS elevated the <em>protein</em> expression of JUN, additional leading to IR in HepG2 cells. Taken collectively, we exhibit that ROS/JUN is a standard response pathway employed by HepG2 cells towards FFA-regulated IR.
The roles of microbial merchandise in the growth of colorectal most cancers: a overview
A big quantity of microbes exist in the intestine and they’ve the skill to course of and make the most of ingested meals. It has been reported that their merchandise are concerned in colorectal most cancers growth. The molecular mechanisms which underlie the relationship between intestine microbial merchandise and CRC are nonetheless not totally understood. The function of some microbial merchandise in CRC is especially controversial. Elucidating the results of intestine microbiota merchandise on CRC and their potential mechanisms is important for CRC prevention and remedy.
![Integrated transcriptomics and metabolomics analyses reveal benzo[a]pyrene enhances the toxicity of mercury to the Manila clam, Ruditapes philippinarum](http://i-309.com/wp-content/uploads/2021/03/WhatsApp-Image-2020-12-09-at-10.46.58-AM-300x146.jpeg)
In this overview, latest research are examined so as to describe the contribution metabolites and toxicants that are produced by intestine microbes make to CRC, primarily specializing in the concerned molecular mechanisms.<b>Abbreviations</b>: CRC: colorectal most cancers; SCFAs: brief chain fatty acids; HDAC: histone deacetylase; <em>TCA</em> cycle: tricarboxylic acid cycle; CoA: cytosolic acyl coenzyme A; SCAD: brief chain acyl CoA dehydrogenase; HDAC: histone deacetylase; MiR-92a: microRNA-92a; KLF4: kruppel-like issue; PTEN: phosphatase and tensin homolog; PI<em>3</em>Okay: phosphoinositide <em>3</em>-kinase; PIP2: phosphatidylinositol 4, 5-biphosphate; PIP<em>3</em>: phosphatidylinositol-<em>3</em>,4,5-triphosphate;
Akt1: <em>protein</em> kinase B subtype α; ERK1/2: extracellular signal-regulated kinases half of; EMT: epithelial-to-mesenchymal transition; NEDD9: neural precursor cell expressed developmentally down-regulated9; CAS: Crk-associated substrate; JNK: c-Jun N-terminal kinase; PRMT1: <em>protein</em> arginine methyltransferase 1; UDCA: ursodeoxycholic acid; BA: bile acids; CA: cholic acid; CDCA: chenodeoxycholic acid; DCA: deoxycholic acid; LCA: lithocholic acid; CSCs: most cancers stem cells; MHC: main histocompatibility; NF-κB: NF-kappaB; GPR: G <em>protein</em>-coupled receptors; ROS: reactive oxygen species; RNS: reactive nitrogen substances; BER: base excision restore;
 MIP-3 alpha, CCL20, human |
|
RC315-31 |
Bio Basic |
5ug |
EUR 104.38 |
|
|
 Anti-MIP-3 alpha Antibody Biotin Conjugated |
|
B00748-1 |
BosterBio |
100ug |
EUR 432 |
|
Description: Rabbit Polyclonal MIP-3 alpha Antibody Biotin Conjugated. Validated in WB and tested in Human. |
 Anti-MIP-1 alpha Antibody |
|
A00405 |
BosterBio |
100ug |
EUR 432 |
|
Description: Rabbit Polyclonal MIP-1 alpha Antibody. Validated in WB and tested in Mouse. |
 Anti-14-3-3 alpha + beta Rabbit Monoclonal Antibody |
|
M02431-3 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal 14-3-3 alpha + beta Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
 Anti- Alpha-Synuclein Antibody |
|
M00215-3 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal Alpha-Synuclein Antibody. Validated in IF, IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat. |
 Anti-TNF alpha Antibody |
|
A00002-3 |
BosterBio |
100ug/vial |
EUR 294 |
 MIP-3 alpha Recombinant Protein |
|
40-353-0005mg |
ProSci |
0.005 mg |
EUR 259.25 |
|
Description: MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and signals through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant murine MIP-3 alpha is a 7.9 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-3 alpha Recombinant Protein |
|
40-353-002mg |
ProSci |
0.02 mg |
EUR 364.25 |
|
Description: MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and signals through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant murine MIP-3 alpha is a 7.9 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-3 alpha Recombinant Protein |
|
40-380-0005mg |
ProSci |
0.005 mg |
EUR 259.25 |
|
Description: MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 alpha is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-3 alpha Recombinant Protein |
|
40-380-002mg |
ProSci |
0.02 mg |
EUR 364.25 |
|
Description: MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 alpha is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
 Anti-IL36 alpha/IL36A Antibody |
|
A09802-3 |
BosterBio |
100ug/vial |
EUR 334 |
, Human) MIP-3-alpha/CCL20 (CHO-expressed), Human |
|
HY-P7260 |
MedChemExpress |
10ug |
EUR 268 |
 Human MIP-3 alpha/CCL20 ELISA Kit |
|
RK00207 |
Abclonal |
96 Tests |
EUR 521 |
 Protein) Recombinant Human MIP-3 Alpha (CCL20) Protein |
|
PROTP78556-2 |
BosterBio |
20ug |
EUR 317 |
|
Description: MIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3α is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
 Rabbit Polyclonal antibody Anti-CRBN |
|
Anti-CRBN |
ImmunoStep |
50 µg |
EUR 349 |
 MIP-1 alpha, CCL3, human |
|
RC315-14 |
Bio Basic |
5ug |
EUR 104.38 |
|
|
 Anti-Hsp90 alpha Rabbit Monoclonal Antibody |
|
M01103-3 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal Hsp90 alpha Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat. |
 Anti-Fibrinogen alpha chain/FGA Antibody |
|
A00816-3 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-AMPK alpha 1/PRKAA1 Antibody |
|
A00994-3 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-Alpha 1 microglobulin/AMBP Antibody |
|
A02419-3 |
BosterBio |
100ug/vial |
EUR 334 |
 anti- MIP-3-beta antibody |
|
FNab05194 |
FN Test |
100µg |
EUR 505.25 |
|
|
|
Description: Antibody raised against MIP-3-beta |
 IgG (Clone #3)) Mouse Monoclonal anti-PEG (backbone specific) IgG (Clone #3) |
|
PEG13-M-3 |
Alpha Diagnostics |
100 ug |
EUR 482 |
) Mouse Monoclonal anti-Clostridium difficile toxin A IgG (Clone #3) |
|
CDTA12-M-3 |
Alpha Diagnostics |
100 ug |
EUR 482 |
 MIP-1 alpha Antibody |
|
20-abx148975 |
Abbexa |
|
|
|
|
MIP-1 alpha Antibody |
|
45363-100ul |
SAB |
100ul |
EUR 252 |
MIP-1 alpha Antibody |
|
45363-50ul |
SAB |
50ul |
EUR 187 |
MIP-1 alpha Antibody |
|
DF8572 |
Affbiotech |
200ul |
EUR 304 |
|
Description: MIP-1 alpha Antibody detects endogenous levels of total MIP-1 alpha. |
 MIP-1-alpha Antibody |
|
5246-100 |
Biovision |
|
EUR 338 |
 MIP 1 alpha antibody |
|
20R-1788 |
Fitzgerald |
100 ug |
EUR 673 |
|
Description: Rabbit polyclonal MIP 1 alpha antibody |
 Anti-Alpha Internexin INA Intermediate Neurofilament Antibody |
|
M03756-3 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal Alpha Internexin INA Intermediate Neurofilament Antibody. Validated in IF, IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat. |
 ELISA kit for Human MIP-3 Alpha/CCL20 |
|
EK5191 |
SAB |
96 tests |
EUR 553 |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of Human MIP-3 Alpha/CCL20 in samples from serum, plasma, tissue homogenates and other biological fluids. |
 Anti-MIP antibody |
|
STJ24556 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13. |
 anti- MIP antibody |
|
FNab05193 |
FN Test |
100µg |
EUR 548.75 |
|
|
|
Description: Antibody raised against MIP |
 Mouse anti-dsDNA IgG3-specific ELISA Kit, 96 tests, Quantitative |
|
5120-3 |
Alpha Diagnostics |
1 kit |
EUR 712 |
, IgG clone 3 aff pure) Monoclonal anti-human Alpha (FSH-Alpha), IgG clone 3 aff pure |
|
FSHA12-M |
Alpha Diagnostics |
1 mg |
EUR 482 |
 Anti-ER alpha Rabbit Monoclonal Antibody, Clone#RM292 |
|
M00057-3 |
BosterBio |
100uL |
EUR 415 |
|
Description: Anti-ER alpha Rabbit Monoclonal Antibody, Clone#RM292 tested in WB, IHC, reactive to Human |
 Anti-alpha smooth muscle Actin Rabbit Monoclonal Antibody |
|
M01072-3 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal alpha smooth muscle Actin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
, Rat) MIP-3-alpha/CCL20 (HEK293-expressed), Rat |
|
HY-P7261 |
MedChemExpress |
10ug |
EUR 268 |
 Protein) Recombinant Murine MIP-3 Alpha (CCL20) Protein |
|
PROTO89093-1 |
BosterBio |
20ug |
EUR 317 |
|
Description: MIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and signals through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant murine MIP-3α is a 7.9 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
 Mouse MIP-3 alpha/CCL20 ELISA Kit |
|
LF-EK50839 |
Abfrontier |
1×96T |
EUR 648 |
 ELISA Kit) MIP-1 alpha (human) ELISA Kit |
|
K4784-100 |
Biovision |
100 assays |
EUR 834 |
|
|
|
Description: Sensitive, Colorimetric Assay |
 MIP-3, CCL23, human |
|
RC315-34 |
Bio Basic |
5ug |
EUR 104.38 |
|
|
 antiserum) Rabbit Anti-Human Fodrin-alpha (spectrin-alpha) antiserum |
|
FOD11-S |
Alpha Diagnostics |
100 ul |
EUR 457 |
 MIP-1 alpha Conjugated Antibody |
|
C45363 |
SAB |
100ul |
EUR 397 |
 MIP-1 alpha Blocking Peptide |
|
DF8572-BP |
Affbiotech |
1mg |
EUR 195 |
 MIP-1 alpha Recombinant Protein |
|
40-337-0002mg |
ProSci |
0.002 mg |
EUR 259.25 |
|
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant murine MIP-1 alpha is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 alpha Recombinant Protein |
|
40-337-001mg |
ProSci |
0.01 mg |
EUR 364.25 |
|
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant murine MIP-1 alpha is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 alpha Recombinant Protein |
|
40-364-0005mg |
ProSci |
0.005 mg |
EUR 259.25 |
|
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant human MIP-1 alpha is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 alpha Recombinant Protein |
|
40-364-002mg |
ProSci |
0.02 mg |
EUR 364.25 |
|
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant human MIP-1 alpha is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 alpha Recombinant Protein |
|
40-412-0005mg |
ProSci |
0.005 mg |
EUR 259.25 |
|
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1 alpha is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 alpha Recombinant Protein |
|
40-412-002mg |
ProSci |
0.02 mg |
EUR 364.25 |
|
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1 alpha is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
 Rabbit Monoclonal Antibody, Clone#RM318) Anti-Acetyl-alpha-Tubulin (Lys40) Rabbit Monoclonal Antibody, Clone#RM318 |
|
M08382-3 |
BosterBio |
100uL |
EUR 455 |
|
Description: Anti-Acetyl-alpha-Tubulin (Lys40) Rabbit Monoclonal Antibody, Clone#RM318 tested in WB, ICC, reactive to All Vertebrates |
 Rabbit Anti Rat Mip-1 Alpha Polyclonal Antibody,Biotin |
|
CPBT-65210RR |
Creative Diagnostics |
50 µg |
EUR 881 |
 Anti-MIP-5 Antibody |
|
A05563 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for MIP-5 Antibody (CCL15) detection.tested for IHC in Human. |
 Anti-MIP-1b Antibody |
|
A16621 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for MIP-1b Antibody (CCL4L1) detection. Tested with WB in Human. |
 Anti-MIP- beta antibody |
|
STJ94131 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to MIP-3beta. |
 Anti-MIP-T3 antibody |
|
STJ94133 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to MIP-T3. |
 Anti-MIP-5 antibody |
|
STJ98780 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to MIP-5. |
Anti-MIP- beta antibody |
|
STJ96572 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to MIP-1beta. |
 Anti-MIP-1b antibody |
|
STJ97347 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to MIP-1b. |
 anti- MIP-3α antibody |
|
FNab09791 |
FN Test |
100µg |
EUR 548.75 |
|
|
|
Description: Antibody raised against MIP-3α |
 (OKBB00399)) MIP-3 alpha/CCL20 ELISA Kit (Mouse) (OKBB00399) |
|
OKBB00399 |
Aviva Systems Biology |
96 Wells |
EUR 505 |
|
Description: Description of target: Macrophage Inflammatory Protein 3α (MIP3α), also called Chemokine, cc motif, ligand 20 (CCL20). The MIP-3alpha/CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3α is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3α/CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin. And Alanine MIP-3α and Serine MIP-3α, the two forms of MIP3α, that differ by one amino acid at the predicted signal peptide cleavage site. Both of them were chemically synthesized and tested for biological activity. And both flu antigen plus IL-2-activated CD4 (+) and CD8 (+) T lymphoblasts and cord blood-derived dendritic cells responded to Ser and Ala MIP-3α.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 1 pg/mL |
 ELISA kit for Mouse MIP-3 Alpha/CCL20 |
|
EK5192 |
SAB |
96 tests |
EUR 553 |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse MIP-3 Alpha/CCL20 in samples from serum, plasma, tissue homogenates and other biological fluids. |
 ELISA kit for Rat MIP-3 Alpha/CCL20 |
|
EK5193 |
SAB |
96 tests |
EUR 553 |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat MIP-3 Alpha/CCL20 in samples from serum, plasma, tissue homogenates and other biological fluids. |
) ELISA kit for Human MIP-3? (Macrophage Inflammatory Protein 3 Alpha) |
|
E-EL-H0027 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 534 |
|
|
|
Description: A sandwich ELISA kit for quantitative measurement of Human MIP-3? (Macrophage Inflammatory Protein 3 Alpha) in samples from Serum, Plasma, Cell supernatant |
) CLIA kit for Human MIP-3? (Macrophage Inflammatory Protein 3 Alpha) |
|
E-CL-H0027 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 584 |
|
|
|
Description: A sandwich CLIA kit for quantitative measurement of Human MIP-3? (Macrophage Inflammatory Protein 3 Alpha) in samples from Serum, Plasma, Cell supernatant |
, Human) MIP-1-alpha/CCL3 (CHO-expressed), Human |
|
HY-P7254 |
MedChemExpress |
50ug |
EUR 533 |
DNA: deoxyribonucleic acid; EGFR: epidermal progress issue receptor; MAPK: mitogen activated <em>protein</em> kinase; ERKs: extracellular sign regulated kinases; AKT: <em>protein</em> kinase B; PA: phosphatidic acid; TMAO: trimethylamine n-oxide; TMA: trimethylamine; FMO<em>3</em>: flavin-containing monooxygenase <em>3</em>; H<sub>2</sub>S: Hydrogen sulfide; SRB: sulfate-reducing micro organism; IBDs: inflammatory bowel illnesses; NSAID: non-steroidal anti-inflammatory medication; BFT: fragile bacteroides toxin; ETBF: enterotoxigenic fragile bacteroides; E-cadherin: extracellular area of intercellular adhesive <em>protein</em>; CEC: colonic epithelial cells; SMOX: spermine oxidase; SMO: smoothened; Stat<em>3</em>: sign transducer and activator of transcription <em>3</em>; Th17: T helper cell 17; IL17: interleukin 17; AA: amino acid; TCF: transcription issue; CDT: cytolethal distending toxin; PD-L1: programmed cell dying 1 ligand 1.
![Integrated transcriptomics and metabolomics analyses reveal benzo[a]pyrene enhances the toxicity of mercury to the Manila clam, Ruditapes philippinarum](http://i-309.com/wp-content/uploads/2021/03/WhatsApp-Image-2020-12-09-at-10.46.58-AM-1024x497.jpeg)