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PP1-α Polyclonal Antibody

PP-1A; PPP1A; MGC1674; MGC15877; PP1alpha; PPP1CA

Product Name

protein phosphatase 1, catalytic subunit, alpha isozyme: PPP1CA

Price

 150  €/ 200 µg

   

Antigen

 

Primary source                    

Alfa isoform of human PP-1 catalytic subunit was used as an antigen

( Gčne 5499 )

HGNC:9281

   

Gčne type   

See related

Protéin Coding

Ensembl:ENSMUSG00000004842

Usage

Western Blot ( 1/500 ) , ELISA, immunoprecipitation.

   

Raised in

Rabbit

Clonality

Polyclonal

Form

Crude serum

Storage instructions

Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Expiration

20/04/2016

 

RefSeq status REVIEWED

Organism Homo sapiens 

Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo

Summary The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]