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TRANSIL® RSA Binding Kit

A ready-to-use kit for rapid assessment of drug candidates' binding to rat serum albumin (RSA)

A novel ready-to-use binding kit designed to assess the binding of drugs to rat serum albumin (RSA). The affinity of a drug candidate to plasma proteins is a true measurement of the free fraction of a drug candidate in plasma.

Benefits

  • Fast, requiring only 2 minutes for incubation.
  • Accurate. Measures the affinity of the drug candidate to rat serum albumin (RSA), a true measurement of the free fraction in plasma, capable of producing pharmacological effects.
  • Reliable with highly reproducible results, and robust correlation to the gold standard equilibrium dialysis method (end-point measurement). Fully quality-controlled plasma protein binding estimates.
  • Ready-to-use format plated in 96-well or ready-to-use tubes in strips of 8. Kit requires only addition of test material, 2-minute incubation, and quantification.
  • Flexible. Enables physiology based modeling (e.g Simcyp) by providing affinity input data. Format is adaptable to automation.

Product Information

 

Product Number Product Name Format
TPB-0220-0096 Transil® RSA Binding Kit 96-well plate
TPB-0220-1196 Transil® RSA Binding Kit 96-well (strips)